Search

Now showing items 1-2 of 2

Flk1+ and VE-Cadherin+ Endothelial Cells Derived from iPSCs Recapitulates Vascular Development during Differentiation and Display Similar Angiogenic Potential as ESC-Derived Cells

Kohler, Erin E; Wary, Kishore K; Li, Fei; Chatterjee, Ishita; Urao, Norifumi; Toth, Peter T; Ushio-Fukai, Masuko; Rehman, Jalees; Park, Changwon; Malik, Asrar B (PLoS One, 2014-01-05)

This work was supported by grants from the National Institutes of Health to KKW (HL079356), MUF (HL112293), JR (GM094220), and ABM (HL090152), and awards from the American Heart Association to EEK (12PRE1208000) and KKW ...

The redox‐sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation

Di, Anke; Gao, Xiao‐Pei; Qian, Feng; Kawamura, Takeshi; Han, Jin; Hecquet, Claudie; Ye, Richard D; Vogel, Stephen M; Malik, Asrar B (Nature Publishing Group, 2011)

The NADPH oxidase activity of phagocytes and its generation of reactive oxygen species (ROS) is critical for host‐defense, but ROS overproduction can also lead to inflammation and tissue injury. Here we report that TRPM2, ...