Periodontics, Department of
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Recent Submissions
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Periodontal Disease and Preterm Birth, is There any Relationship?
(Wolters Kluwers, 2016-07-13)Aim: Prematurity and low birth weight are major causes of neonatal morbidity, mortality and long-term disability. The purpose of this study was to determine if an association exists between periodontal disease and preterm ... -
Management of Thin Gingival Biotype with Hard and Soft Tissue Augmentation Post Orthodontic Treatment: A Case Report.
(Horizon Research Publishing, 2015-03)Background: In the United States, orthodontic therapy has become a common phase in people’s lives. Patients seek treatment for esthetic and functional reasons. As with most treatment modalities, it has its own risks and ... -
Real-Time Diffusion of Information on Twitter and the Financial Markets.
(Public Library of Science, 2016-08-09)Do spikes in Twitter chatter about a firm precede unusual stock market trading activity for that firm? If so, Twitter activity may provide useful information about impending financial market activity in real-time. We ... -
Aberrant wound healing in an epidermal interleukin-4 transgenic mouse model of atopic dermatitis
(Public Library of Science, 2016-01-11)Wound healing in a pre-existing Th2-dominated skin milieu was assessed by using an epidermal specific interleukin-4 (IL-4) transgenic (Tg) mouse model, which develops a pruritic inflammatory skin condition resembling human ... -
UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development
(Public Library of Science, 2015-11)The Ufm1 conjugation system is an ubiquitin-like modification system that consists of Ufm1, Uba5 (E1), Ufc1 (E2), and less defined E3 ligase(s) and targets. The biological importance of this system is highlighted by its ... -
MiR-142-3p is a RANKL-dependent inducer of cell death in osteoclasts.
(Nature Publishing Group, 2016-04-26)MicroRNA are small, non-coding, single-stranded RNAs that are estimated to regulate ~60% of the human genome. MiRNA profiling of monocyte-to-osteoclast differentiation identified miR-142-3p as a miRNA that is significantly, ... -
Saturation mutagenesis of the antithrombin reactive center loop P14 residue supports a three-step mechanism of heparin allosteric activation involving intermediate and fully activated states.
(American Society for Biochemistry and Molecular Biology, 2015-11)Past studies have suggested that a key feature of the mechanism of heparin allosteric activation of the anticoagulant serpin, antithrombin, is the release of the reactive center loop P14 residue from a native state stabilizing ... -
UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development.
(Public Library of Science, 2015-11-06)The Ufm1 conjugation system is an ubiquitin-like modification system that consists of Ufm1, Uba5 (E1), Ufc1 (E2), and less defined E3 ligase(s) and targets. The biological importance of this system is highlighted by its ... -
MiRNA-Target Interaction Reveals Cell-Specific Post-Transcriptional Regulation in Mammalian Cell Lines.
(MDPI, 2016-01-08)MicroRNAs are 18-22 nucleotides long, non-coding RNAs that bind transcripts with complementary sequences leading to either mRNA degradation or translational suppression. However, the inherent differences in preferred mode ... -
TLR4 Expression by Liver Resident Cells Mediates the Development of Glucose Intolerance and Insulin Resistance in Experimental Periodontitis.
(Public Library of Science, 2015-08-28)BACKGROUND: Results from epidemiological studies indicate a close association between periodontitis and type 2 diabetes mellitus. However, the mechanism linking periodontitis to glucose intolerance (GI) and insulin ... -
The Utility of Hybrid Promotion and Tenure Tracks for Dental School Faculty
(American Dental Education Association, 2013-08)The promotion and tenure process for faculty members varies, by design, for different disciplines, departments, and academic institutions. For many faculty members in U.S. dental schools, the process may thus appear nebulous ... -
Identification of serpin determinants of specificity and selectivity for furin inhibition through studies of α1PDX (α1-protease inhibitor Portland)-serpin B8 and furin active-site loop chimeras.
(American Society for Biochemistry and Molecular Biology, 2013-07)α1-Protease inhibitor Portland (α1PDX) is an engineered serpin family inhibitor of the proprotein convertase (PC), furin, that exhibits high specificity but limited selectivity for inhibiting furin over other PC family ... -
Acute Pain Speeds Skin Barrier Recovery in Healthy Men and Women
(Elsevier, 2012-12)Objective. Psychological stress is known to impair skin barrier recovery, but little is known about the impact of pain on skin healing processes. Our primary goals were to examine the degree to which acute pain affects ... -
Identification of Microbial and Proteomic Biomarkers in Early Childhood Caries
(Hindawi Publishing Corporation, 2011)The purpose of this study was to provide a univariate and multivariate analysis of genomic microbial data and salivary massspectrometry proteomic profiles for dental caries outcomes. In order to determine potential useful ... -
The Effects of 17-beta Estradiol on Enhancing Proliferation of Human Bone Marrow Mesenchymal Stromal Cells In Vitro
(Mary Ann Liebert, 2011-05)Human bone marrow mesenchymal stromal cells (MSCs) with self-renewal and multiple differentiation potentials are considered a possible cell source for tissue engineering and regenerative medicine. However, the limited ...
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