Brodie Laboratory for Craniofacial Genetics
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Amelogenin Supramolecular Assembly in Nanospheres Defined by a Complex Helix-Coil-PPII Helix 3D-Structure (Public Library of Science, 2011-10)Tooth enamel, the hardest material in the human body, is formed within a self-assembled matrix consisting mostly of amelogenin proteins. Here we have determined the complete mouse amelogenin structure under physiological ...
Apatite Microtopographies Instruct Signaling Tapestries for Progenitor-Driven New Attachment of Teeth (Mary Ann Liebert, 2011-02)Dimension and structure of extracellular matrix surfaces have powerful influences on cell shape, adhesion, and gene expression. Here we show that natural tooth root topographies induce integrin-mediated extracellular matrix ...