• Analysis of Factors Predicting Surgical Intervention and Associated Costs in Pediatric Breast Masses: A Single Center Study. 

  Englert, Graham, E.; Ares, Guillermo; Henricks, Andrea; Rychlik, Karen; Hunter, Catherine, J. (Springer Verlag, 2018-04-11)

  PURPOSE: Finding a breast mass in a child provokes apprehension in parents, especially in those with a family history of breast cancer. Clinicians must decide between serial imaging or biopsy of the mass. Herein, we ...

• Sphincter-Sparing Anal Fistula Repair: Are We Getting Better? 

  Sugrue, J; Mantilla, N; Abcarian, A; Kochar, K; Marecik, S; Chaudhry, V; Mellgren, A; Nordenstam, J (LIPPINCOTT WILLIAMS & WILKINS, 2017-10)

  BACKGROUND: Sphincter-sparing repairs are commonly used to treat anal fistulas with significant muscle involvement. OBJECTIVE: The current study evaluates the trends and efficacy of sphincter-sparing repairs and ...

• The epigenetic drug Trichostatin A ameliorates experimental autoimmune encephalomyelitis via T cell tolerance induction and impaired influx of T cells into the spinal cord 

  Jayaraman, A; Jayaraman, S; Soni, A; Prabhakar, BS; Holterman, M (Academic Press Inc., 2017-12)

  Multiple sclerosis is a T cell mediated chronic demyelinating disease of the central nervous system. Although currently available therapies reduce relapses, they do not facilitate tolerization of myelin antigen-specific T ...

• No clinical benefit from routine histologic examination of stapler doughnuts at low anterior resection for rectal cancer 

  Dagbert, Francois; Park, Park; Sugrue, Jeremy; Marecik, Slawomir; Prasad, Leela M.; Chaudhry, Vivek; Blumetti, Jennifer; Emmadi, Rajyasree; Mellgren, Anders; Nordenstam, Johan (MOSBY-ELSEVIER, 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA, 2017-07)

  Background. The aim of this study was to evaluate the clinical utility and cost-effectiveness of routine histologic examination of the doughnuts from stapled anastomoses in patients undergoing a low anterior resection for ...

• Pathogenesis and persistence of cryptoglandular anal fistula: a systematic review 

  Sugrue, J; Nordenstam, J; Abcarian, H; Bartholomew, A; Schwartz, JL; Mellgren, A; Tozer, PJ (Springer Verlag, 2017-06)

  Anal fistulas continue to be a problem for patients and surgeons alike despite scientific advances. While patient and anatomical characteristics are important to surgeons who are evaluating patients with anal fistulas, ...

• The Potential for Emerging Microbiome-Mediated Therapeutics in Asthma 

  Ozturk, AB; Turturice, BA; Perkins, DL; Finn, PW (Current Medicine Group, 2017-09)

  Purpose of Review: In terms of immune regulating functions, analysis of the microbiome has led the development of therapeutic strategies that may be applicable to asthma management. This review summarizes the current ...

• Effect of preadmission bowel preparation on outcomes of elective colorectal procedures in young children 

  Ares, Guillermo, J.; Helenowski, Irene; Hunter, Catherine, J.; Madonna, Marybeth; Reynolds, Marleta; Lautz, Timothy (Elsevier, 2017-03-30)

  Background: The utility of mechanical bowel preparation (MBP) to minimize infectious complications in elective colorectal surgery is contentious. Though data is scarce in children, adult studies suggest a benefit to MBP ...

• SINGLE CENTER EXPERIENCE WITH ROBOTIC KIDNEY TRANSPLANTATION FOR RECIPIENTS WITH BMI 40 kg/m2: A COMPARISON WITH THE UNOS REGISTRY. 

  Garcia-Roca, Raquel; Garcia- Aroz, Sandra; Tzvetanov, Ivo; Jeon, Hoombae; Oberholzer, Jose; Benedetti, Enrico (Lippincott, Williams & Wilkins, 2017-01)

  BACKGROUND: Obesity represents a barrier to kidney transplantation, but the increasing prevalence among renal failure patients has forced some centers to carefully consider such candidates. Morbidly obese patients may be ...

• The Science and Necessity of Using Animal Models in the Study of Necrotizing Enterocolitis 

  Ares, Guillermo, J.; McElroy, Steven, J.; Hunter, Catherine, J. (Elsevier, 2018-02)

  Necrotizing enterocolitis (NEC) remains one of the highest causes of mortality and of acute and long-term morbidity in premature infants. Multiple factors are involved in the pathophysiology of NEC including the immaturity ...

• When Is It Safe to Return to Driving After Spinal Surgery? 

  Scott, TP; Pannel, W; Savin, D; Ngo, SS; Ellerman, J; Toy, K; Daubs, MD; Lu, D; Wang, JC (Thieme Publishing, 2015-08)

  Study Design Prospective study. Objective Surgeons' recommendations for a safe return to driving following cervical and lumbar surgery vary and are based on empirical data. Driver reaction time (DRT) is an objective measure ...

• Awareness of preventive medication among women at high risk for breast cancer and their willingness to consider transdermal or oral tamoxifen: A focus group study 

  Karavites, L. C.; Allu, S.; Khan, S. A.; Kaiser, K. (BioMed Central, 2015-11-09)

  Background: Despite demonstrated efficacy, acceptance of selective estrogen receptor modulators (SERMs), such as tamoxifen, for breast cancer risk reduction remains low. Delivering SERMs via local transdermal therapy (LTT) ...

• Concurrent congenital peritoneopericardial diaphragmatic hernia and bochdalek hernia in a neonate 

  Bean, Jonathan F.; Kort, Chad A.; Radhakrishnan, Jayant (SpringerOpen, 2014)

  We present the first report of a neonate with, concurrent left sided Bochdalek hernia and peritoneopericardial diaphragmatic hernia.

• Esophageal Stent Migration as a Cause of Severe Upper Airway Obstruction 

  Sloan, Mark A.; Hauter, William E.; Sloan, Paul A.; Hafner, John A. (Dove Medical Press, 2014-07-15)

  Self-expandable metal esophageal stents (SEMS) are used to provide symptomatic relief of dysphagia, particularly in cancer patients. The advancement of covered SEMS stents has decreased the rate of tumor in-growth complications, ...

• Diabetes and Coronary Heart Disease: A Risk Factor for the Global Epidemic 

  Chiha, Maguy; Njeim, Mario; Chedrawy, Edgar G. (Hindawi Publishing Corporation, 2012-09)

  Cardiovascular disease remains a leading cause of death in the United States and the world. In this we will paper focus on type 2 diabetes mellitus as a risk factor for coronary heart disease, review the mechanisms of ...

• Hand-assisted robotic right donor nephrectomy in patient with total situs inversus: A case report. 

  Gonzalez-Heredia, R; Garcia-Roca, R; Benedetti, E (Elsevier: Creative Commons, 2016)

  Total situs inversus" is an infrequent congenital condition. The robot has been already proved as a safe and attractive approach for living donor nephrectomies. We report here the first right donor nephrectomy in a patient ...

• A microfluidic array for real-time live-cell imaging of human and rodent pancreatic islets. 

  Nourmohammadzadeh, M; Xing, Y; Lee, JW; Bochenek, MA; Mendoza-Elias, JE; McGarrigle, JJ; Marchese, E; Chun-Chieh, Y; Eddington, DT; Oberholzer, J; Wang, Y (Royal Society of Chemistry, 2016-04-12)

  In this study, we present a microfluidic array for high-resolution imaging of individual pancreatic islets. The device is based on hydrodynamic trapping principle and enables real-time analysis of islet cellular responses ...

• Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer. 

  Zuberi, M; Khan, I; Mir, R; Gandhi, G; Ray, PC; Saxena, A (Public Library of Science, 2016-04-19)

  MicroRNAs (miRNAs) have been found to be dysregulated in epithelial ovarian cancer (EOC) and may function as either tumor suppressor genes (TSGs) or as oncogenes. Hypermethylation of miRNA silences the tumour suppressive ...

• De novo gastric adenocarcinoma 1 year after sleeve gastrectomy in a transplant patient. 

  Masrur, M; Elli, E; Gonzalez-Ciccarelli, LF; Giulianotti, PC (Elsevier, 2016)

  Abstract INTRODUCTION: It has been reported in the literature that upper gastrointestinal malignancies after bariatric surgery are mostly gastro-esophageal, although it is not clear whether bariatric surgery represents ...

• SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β. 

  Sundaresan, NR; Bindu, S; Pillai, VB; Samant, S; Pan, Y; Huang, JY; Gupta, M; Nagalingam, RS; Wolfgeher, D; Verdin, E; Gupta, MP (American Society for Microbiology, 2015-12-14)

  Tissue fibrosis is a major cause of organ dysfunction during chronic diseases and aging. A critical step in this process is transforming growth factor 1 (TGF-1)-mediated transformation of fibroblasts into myofibroblasts, ...

• Diazoxide, a KATP Channel Opener, Prevents Ischemia‐Reperfusion Injury in Rodent Pancreatic Islets. 

  Wang, Y.; Wang, S.; Harvat, T.; Kinzer, K.; Zhang, L.; Feng, F.; Qi, M.; Oberholzer, J. (Cognizant Communication Corporation, 2015-01)

  Diazoxide (DZ) is a pharmacological opener of ATP-sensitive K + channels that has been used for mimicking ischemic preconditioning and shows protection against ischemic damage. Here we investigated whether diazoxide ...

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