• Parent and adolescent attitudes towards preventive care and confidentiality 

  Song, Xiaoyu; Klein, Jonathan, D.; Yan, Hanying; Catallozzi, Marina; Wang, Xianling; Heitel, Jenifer; Kaseeska, Kristen; Gorzkowski, Julie; Santelli, John, S. (Elsevier, 2019-02)

  Objective Little is known about whether parents and adolescents agree in their attitudes towards preventive care, private time and confidentiality for adolescent care. Methods We surveyed a nationally representative ...

• Patient safety morning report: Innovation in teaching core patient safety principles to third-year medical students. 

  Beekman, Michele; Emani, Vamsi, K.; Wolford, Robert; Hanson, Keith; Wickham, Gerald; Aiyer, Meenakshy (Libertas Academica, 2019-03-07)

  Introduction: Patient safety (PS) is one of the most important priorities in modern healthcare systems. Unfortunately, PS education is limited in many medical school curricula. Our objective was to implement an innovative ...

• Public Support for Smoke-Free Section 8 Public Housing 

  McMillen, Robert C.; Winickoff, Jonathan P.; Gottlieb, Mark A.; Tanski, Susanne; Wilson, Karen; Klein, Jonathan D. (SAGE Publications, 2019-02-10)

  As of July 31, 2018, all Housing and Urban Development (HUD) designated Housing Authorities administering public housing must have a smoke-free policies, but this requirement does not extend to Section 8 housing. Section ...

• Chicago Public School Nurses Examine Barriers to School Asthma Care Coordination 

  Pappalardo, Andrea, A.; Paulson, Allison; Bruscato, Robin; Thomas, Leretha; Minier, Mark; Martin, Molly, A. (Wiley, 2018-12-19)

  Objective/Design: Well documented asthma disparities in Chicago pose a continual challenge for the Chicago Public Schools (CPS). Coordinated Health Care for Complex Kids (CHECK) is a health care demonstration project ...

• Adolescent Use of Different E-cigarette Products 

  McMillen, Robert; Tanski, Susanne; Wilson, Karen; Klein, Jonathan, D.; Winickoff, Jonathan, P. (2018-10)

  BACKGROUND: Little is known about the characteristics of electronic cigarettes (e-cigarettes) used by adolescents. Understanding the product landscape of adolescent e-cigarette use may inform counseling and policy ...

• Alpha-Enolase Regulates the Malignant Phenotype of Pulmonary Artery Smooth Muscle Cells via the AMPK-Akt pathway 

  Dai, Jingbo; Zhou, Qiyuan; Chen, Jiwang; Rexius-Hall, Megan, L.; Rehman, Jalees; Zhou, Guofei (Nature Research, 2018-09-21)

  The molecular mechanisms underlying the metabolic shift toward increased glycolysis observed in pulmonary artery smooth muscle cells (PASMC) during the pathogenesis of pulmonary arterial hypertension (PAH) are not fully ...

• Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension 

  Dai, Jingbo; Tang, Haiyang; Zhou, Qiyuan; Chen, Tianji; Li, Jing; Raychaudhuri, Pradip; Yuan, Jason X.-J.; Zhou, Guofei (Elsevier, 2018-11-01)

  Rationale: Forkhead box M1 (FoxM1) is a transcription factor that promotes cell proliferation by regulating a broad spectrum of genes that participate in cell cycle regulation, such as Cyclin B, CDC25B, and Aurora B Kinase. ...

• PAI-1 is a novel component of the miR-17~92 signaling that regulates pulmonary artery smooth muscle cell phenotypes 

  Chen, Tianji; Huang, Jason B.; Dai, Jingbo; Zhou, Qiyuan; Raj, J. Usha; Zhou, Guofei (American Physiological Society, 2018-08-01)

  We have previously reported that miR-17~92 is critically involved in the pathogenesis of pulmonary hypertension (PH). We also identified two novel mR-17/20a direct targets PDLIM5 and PHD2 and elucidated the signaling ...

• Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion 

  Zhou, Q; Dai, J; Chen, T; Dada, LA; Zhang, X; Zhang, W; DeCamp, MM; Winn, RA; Sznajder, JI; Zhou, G (Elsevier Inc., 2017-10)

  Atypical protein kinase C ζ (PKCζ) forms an apico-basal polarity complex with Partitioning Defective (Pard) 3 and Pard6 to regulate normal epithelial cell apico-basolateral polarization. The dissociation of the PKCζ/Pard3/Pard6 ...

• Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis. 

  Zhou Q; Chen T; Zhang W; Bozkanat M; Li Y; Xiao L; van Breemen RB; Christman JW; Sznajder JI; Zhou G (American Thoracic Society, 2016-05)

  We have reported that von Hippel-Lindau protein (pVHL) expression is elevated in human and mouse fibrotic lungs and that overexpression of pVHL stimulates fibroblast proliferation. We sought to determine whether loss of ...

• A survey of steroid-related osteoporosis diagnosis,prevention and treatment practices of pediatric rheumatologists in North America 

  Soybilgic, Arzu; Tesher, Melissa; Wagner-Weiner, Linda; Onel, Karen B. (BioMed Central, 2014-07-09)

  Background: The purpose of our study is to assess practices of North American pediatric rheumatologists regarding monitoring, prevention, and treatment of low bone mineral density (BMD) in children on long-term glucocorticoid ...

• Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study. 

  Hou, L; Barupal, J; Zhang, W; Zheng, Y; Liu, L; Zhang, X; Dou, C; McCracken, JP; Díaz, A; Motta, V; Sanchez-Guerra, M; Wolf, KR; Bertazzi, PA; Schwartz, JD; Wang, S; Baccarelli, AA (National Institute of Environmental Health Sciences, 2016-03)

  BACKGROUND: MicroRNAs (miRNAs) are post-transcriptional gene suppressors and potential mediators of environmental effects. In addition to human miRNAs, viral miRNAs expressed from latent viral sequences are detectable in ...

• MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells. 

  Zeng, Y; Zhang, X; Kang, K; Chen, J; Wu, Z; Huang, J; Lu, W; Chen, Y; Zhang, J; Wang, Z; Zhai, Y; Qu, J; Ramchandran, R; Raj, JU; Wang, J; Gou, D (Nature Publishing Group, 2016-04-28)

  There is growing evidence that microRNAs are implicated in pulmonary arterial hypertension (PAH), but underlying mechanisms remain elusive. Here, we identified that miR-223 was significantly downregulated in chronically ...

• Childhood Poverty and Its Effect on Health and Well-being: Enhancing Training for Learners Across the Medical Education Continuum. 

  Chamberlain, LJ; Hanson, ER; Klass, P; Schickedanz, A; Nakhasi, A; Barnes, MM; Berger, S; Boyd, RW; Dreyer, BP; Meyer, D; Navsaria, V; Rao, S; Klein, M (Elsevier Inc., 2016-04)

  OBJECTIVE: Childhood poverty is unacceptably common in the US and threatens the health, development, and lifelong well-being of millions of children. Health care providers should be prepared through medical curricula to ...

• Results from a community-based trial testing a community health worker asthma intervention in Puerto Rican youth in Chicago. 

  Martin, M.A.; Mosnaim, G.S.; Olson, D.; Swider, S.; Karavolos, K.; Rothschild, S. (Informa Healthcare, 2015-02)

  Abstract Objective: Puerto Rican children suffer disproportionately from asthma. Project CURA tested the efficacy of a community health worker (CHW) intervention to improve use of inhaled corticosteroids (ICS) and reduce ...

• Initial steps for quality improvement of obesity care across divisions at a tertiary care pediatric hospital. 

  Chang, SZ; Beacher, DR; Kwon, S.; McCarville, MA; Binns, HJ; Ariza, A.J. (MDPI, 2014-09-17)

  BACKGROUND: Pediatric subspecialists can participate in the care of obese children. OBJECTIVE: To describe steps to help subspecialty providers initiate quality improvement efforts in obesity care. METHODS: An anonymous ...

• Executive Functioning in Children and Adolescents With Perinatal HIV Infection. 

  Nichols, SL; Brummel, SS; Smith, RA; Garvie, PA; Hunter, SJ; Malee, KM; Kammerer, BL; Wilkins, ML; Rutstein, R; Tassiopoulos, K; Chernoff, MC; Mellins, CA; Pediatric HIVAIDS Cohort Study (Lippincott, Williams & Wilkins, 2015-09)

  Background: Perinatal HIV (PHIV) infection may place youth at risk for impairments in executive functioning (EF). We examined associations of EF with HIV infection, disease severity and other factors among youth with PHIV ...

• Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): exome sequencing of trios, monozygotic twins and tumours. 

  Barclay, SF; Rand, CM; Borch, LA; Nguyen, L; Gray, PA; Gibson, WT; Wilson, RJ; Gordon, PM; Aung, Z; Berry-Kravis, EM; Ize-Ludlow, D; Weese-Mayer, DE; Bech-Hansen, NT (BioMed Central, 2015-08-25)

  BACKGROUND: Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) is thought to be a genetic disease caused by de novo mutations, though causative mutations have yet to ...

• All-Trans Retinoic Acid Induces TGF-β2 in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2. 

  Namachivayam, K; MohanKumar, K; Arbach, D; Jagadeeswaran, R; Jain, SK; Natarajan, V; Mehta, D; Jankov, RP; Maheshwari, A (Public Library of Science, 2015-07-30)

  OBJECTIVE: We have shown previously that preterm infants are at risk of necrotizing enterocolitis (NEC), an inflammatory bowel necrosis typically seen in infants born prior to 32 weeks' gestation, because of the developmental ...

• Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells. 

  Zeng, Y.; Liu, H.; Kang, K.; Wang, Z.; Hui, G.; Zhang, X.; Zhong, J.; Peng, W.; Ramchandran, R.; Raj, JU; Gou, D. (Nature Publishing Group, 2015-07-13)

  There is growing evidence that microRNAs play important roles in cellular responses to hypoxia and in pulmonary hypertensive vascular remodeling, but the exact molecular mechanisms involved are not fully elucidated. In ...

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