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glpX Gene of Mycobacterium tuberculosis: Heterologous Expression, Purification, and Enzymatic Characterization of the Encoded Fructose 1,6-bisphosphatase II
(Humana Press, 2011-03-31)
The glpX gene (Rv1099c) of Mycobacterium tuberculosis (Mtb) encodes Fructose 1,6- bisphosphatase II (FBPase II; EC 18.104.22.168); a key gluconeogenic enzyme. Mtb possesses glpX homologue as the major known FBPase. This study ...
Crystallization and preliminary X-ray characterization of the glpX-encoded class II fructose-1,6-bisphosphatase from Mycobacterium tuberculosis
(International Union of Crystallography, 2011-06)
Fructose-1,6-bisphosphatase (FBPase; EC 22.214.171.124), which is a key enzyme in gluconeogenesis, catalyzes the hydrolysis of fructose 1,6-bisphosphate to form fructose 6-phosphate and orthophosphate. The present investigation ...