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Phytoconstituents from Alpinia purpurata and their in vitro inhibitory activity against Mycobacterium tuberculosis
(Medknow Publications, 2010-10-20)
Alpinia purpurata or red ginger was studied for its phytochemical constituents as part of our growing interest on Philippine Zingiberaceae plants that may exhibit antimycobacterial activity. The hexane and dichloromethane ...
A Two-Step Strategy for the Complementation of M. Tuberculosis Mutants
(Brazilian Genetics Society, 2011)
The sequence of Mycobacterium tuberculosis, completed in 1998, facilitated both the development of genomic tools, and the creation of a number of mycobacterial mutants. These mutants have a wide range of phenotypes, from ...
Glpx gene in mycobacterium tuberculosis is required for in vitro gluconeogenic growth and in vivo survival
(Public Library of Science, 2015-09-23)
Several enzymes involved in central carbon metabolism and gluconeogenesisplay a critical role in survival and pathogenesis of Mycobacterium tuberculosis (Mtb). The only known functional fructose 1,6-bisphosphatase (FBPase) ...