Now showing items 1-3 of 3
glpX Gene of Mycobacterium tuberculosis: Heterologous Expression, Purification, and Enzymatic Characterization of the Encoded Fructose 1,6-bisphosphatase II
(Humana Press, 2011-03-31)
The glpX gene (Rv1099c) of Mycobacterium tuberculosis (Mtb) encodes Fructose 1,6- bisphosphatase II (FBPase II; EC 18.104.22.168); a key gluconeogenic enzyme. Mtb possesses glpX homologue as the major known FBPase. This study ...
Glpx gene in mycobacterium tuberculosis is required for in vitro gluconeogenic growth and in vivo survival
(Public Library of Science, 2015-09-23)
Several enzymes involved in central carbon metabolism and gluconeogenesisplay a critical role in survival and pathogenesis of Mycobacterium tuberculosis (Mtb). The only known functional fructose 1,6-bisphosphatase (FBPase) ...
Crystallization and preliminary X-ray characterization of the glpX-encoded class II fructose-1,6-bisphosphatase from Mycobacterium tuberculosis
(International Union of Crystallography, 2011-06)
Fructose-1,6-bisphosphatase (FBPase; EC 22.214.171.124), which is a key enzyme in gluconeogenesis, catalyzes the hydrolysis of fructose 1,6-bisphosphate to form fructose 6-phosphate and orthophosphate. The present investigation ...