Now showing items 1-6 of 6
Expression and Function of NUMB in Odontogenesis
(Hindawi Publishing Corporation, 2013)
NUMB is a multifunctional protein implicated to function in self-renewal and differentiation of progenitors in several tissues. To characterize the transcripts and to analyze the expression pattern of NUMB in odontogenesis, ...
Odontogenic Induction of Dental Stem Cells by Extracellular Matrix-Inspired Three-Dimensional Scaffold
(Mary Ann Liebert, 2014-01)
Currently, root canal therapy is the only clinical treatment available to treat damaged or necrotic dental pulp tissue arising from caries. This treatment results in the loss of tooth vitality. Somatic dental stem cell-based ...
Biomimetic Extracellular Matrix-Incorporated Scaffold Induces Osteogenic Gene Expression in Human Marrow Stromal Cells
(Mary Ann Liebert, 2012-02)
Engineering biomaterials mimicking the biofunctionality of the extracellular matrix (ECM) is important in instructing and eliciting cell response. The native ECM is highly dynamic and has been shown to support ...
Protein templates in hard tissue engineering
Biomineralization processes such as formation of bones and teeth require controlled mineral deposition and self-assembly into hierarchical biocomposites with unique mechanical properties. Ideal biomaterials for regeneration ...
Stress Chaperone GRP-78 Functions in Mineralized Matrix Formation
(American Society for Biochemistry and Molecular Biology, 2011-03)
Mineralized matrix formation is a well-orchestrated event requiring several players. Glucose regulated protein-78 (GRP-78) is an endoplasmic reticulum chaperone protein that has been implicated in functional roles ranging ...
Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen
(Hindawi Publishing Corporation, 2012)
The contact system of coagulation can be activated when in contact with biomaterials. As collagen is being tested in novel biomaterials in this study, we have investigated how type IV collagen affects plasma kallikrein and ...