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    • Enhanced Ca2+-sensing Receptor Function in Idiopathic Pulmonary Arterial Hypertension 

      Yamamura, Aya; Guo, Qiang; Yamamura, Hisao; Zimnicka, Adriana M.; Pohl, Nicole M.; Smith, Kimberly A.; Fernandez, Ruby A.; Zeifman, Amy; Makino, Ayako; Dong, Hui; Yuan, Jason X.-J. (American Heart Association, 2012-08)
      Rationale: A rise in cytosolic Ca2+ concentration ([Ca2+]cyt) in pulmonary arterial smooth muscle cells (PASMC) is an important stimulus for pulmonary vasoconstriction and vascular remodeling. Increased resting [Ca2+]cyt ...