Configuration of membrane-bound proteins by x-ray reflectivity
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| Title: |
Configuration of membrane-bound proteins by x-ray reflectivity |
| Author(s): |
Chen, Chiu-Hao; Ma´lkova, Sa´rka; Cho, Wonhwa; Schlossman, Mark L.
|
| Abstract: |
In this presentation we review our recent work using x-ray reflectivity to determine the configuration of membrane-bound proteins. The reflectivity data is analyzed in terms of the known crystallographic structure of proteins and a slab model representing the lipid layer to yield an electron density
profile of the lipid/protein system. Our recent modified analysis methodology for the lipid/protein system is concisely described in this report. In addition, some results of the configuration of the membrane-bound proteins cPLA2a-C2, p40phox-PX, and PKCa-C2 are highlighted. |
| Issue Date: |
2010-11 |
| Publisher: |
American Institute of Physics |
| Citation Info: |
Chen, C. H., Malkova, S., Cho, W., & Schlossman, M. L. 2011. Configuration of membrane-bound proteins by x-ray reflectivity. Journal of Applied Physics, 110: 102215. DOI: 10.1063/1.3661985 |
| Type: |
Article |
| Description: |
Copyright 2011 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Chen, C. H., Malkova, S., Cho, W., & Schlossman, M. L. 2011. Configuration of membrane-bound proteins by x-ray reflectivity. Journal of Applied Physics, 110(10). and may be found at http://jap.aip.org/resource/1/japiau/v110/i10/p102215_s1.
DOI: 10.1063/1.3661985 |
| URI: |
http://hdl.handle.net/10027/8547
|
| ISSN: |
0021-8979 |
| Sponsor: |
This work was supported by National Science Foundation (NSF) grants (Nos. CHE0315691 and CHE0615929 to M.L.S.) and National Institutes of Health (NIH) grants(GM68849 and GM76581 to W.C.). M.L.S. thanks Dr. Aleksey Tikhonov for help with the X19 C beamline at National
Synchrotron Light Source (NSLS) (Brookhaven National Laboratory), which was partially supported by ChemMat- CARS (supported by NSF-CHE, NSF-DMR, and the Department of Energy (DOE)). The Brookhaven National Laboratory and the NSLS are supported by DOE. |
| Date Available in INDIGO: |
2012-08-18 |
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