Limbal Allograft Transplantation Using Fibrin Glue

Abstract

Limbal transplantation is now widely accepted as the treatment of advanced limbal stem cell deficiency. Herein, we describe a technique for harvesting thin limbal grafts from cadaveric corneoscleral rims and a sutureless method to secure the grafts to the recipient eye using fibrin glue. We report the results of fibrin glue assisted keratolimbal allograft (KLAL) in 19 eyes of 16 patients with the outcome measures of ocular surface stability, visual acuity, and post-operative complications. The results indicate that limbal allograft transplantation can be performed safely and successfully using only fibrin glue to secure the grafts. This can potentially improve surgical efficiency and patient comfort post-operatively.